A healthcare Qualified must be consulted prior to using any drug, changing any diet regime or commencing or discontinuing any system of cure.

Will not utilize a home teaspoon to measure your medicine. It's possible you'll accidently just take too much. Tend not to overfill the measuring system. Rinse your measuring unit with drinking water right after each use.

This medication can dry up and thicken mucus with your lungs, rendering it more difficult to breathe and obvious your lungs. To help avert this impact, drink an abundance of fluids Until or else directed by your health care provider.

Acquire this medication exactly as prescribed to decrease the potential risk of dependancy. Ask your health care provider or pharmacist For additional particulars.

Clinical Things to consider Fetal/Neonatal Adverse Reactions Extended utilization of opioid analgesics all through pregnancy for health care or nonmedical uses may end up in Actual physical dependence while in the neonate and neonatal opioid withdrawal syndrome Soon immediately after birth.

Suitable evaluation of the affected individual, right prescribing procedures, periodic re-analysis of therapy, and appropriate dispensing and storage are proper actions that assistance to limit abuse of opioid medications.

Promethazine with Codeine Oral Solution really should be utilized with warning in patients with bone-marrow melancholy. Leukopenia and agranulocytosis have been described, generally when promethazine is Employed in association with other regarded marrow-toxic agents.

Narcotic analgesics result in histamine release, which seems being answerable for wheals or urticaria at times noticed at the site of injection on parenteral administration.

Promethazine really should be applied cautiously in people with cardiovascular disease or with impairment of liver function.

Codeine might bring about miosis, even in complete darkness. Pinpoint pupils are an indication of opioid overdose but aren't pathognomonic (eg., pontine lesions of hemorrhagic or ischemic origin may well create very similar findings). Marked mydriasis as an alternative to miosis may be witnessed with hypoxia in overdose conditions [see

]. Promethazine Symptoms and signs of overdosage with promethazine range between moderate depression from the central nervous system and cardiovascular system to profound hypotension, respiratory despair, unconsciousness and unexpected Demise.

In Girls with usual codeine metabolism (ordinary CYP2D6 activity), the amount of codeine secreted into human milk is minimal and dose-dependent. There isn't a info on the consequences of the codeine on milk manufacturing.

Store at room temperature faraway from light-weight and dampness. read more Don't keep in the toilet. Do not freeze. Continue to keep all prescription drugs clear of children and pets.

If Promethazine with Codeine Oral Solution is employed for a prolonged interval in a very pregnant girl, advise the affected individual of the chance of neonatal opioid withdrawal syndrome and make sure that correct treatment method will probably be out there [see Warnings and Precautions (five.20)].